Insilico study of Human lung cancer oncogenes and their proteins using different software tools

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G.Anitha Mary
G. Anjan Babu

Abstract

- Early stage lung cancer detection is the first step toward successful clinical therapy, the methods outlined and studied in the present research gives a solution to find the basic reasons for causing lung cancer. Clinicians analyze cancer progression by extracting tumor cell proteins in the blood plasma of the patients. Lung cancer is the leading cause of cancer death in the world. The patient survival rates for 5 years and 10 years remain very low at 14% and 8%, respectively. Though we have many advanced methods like diagnostic imaging and therapy, improvements over the past decade have shown a considerable good results. We report here an approach to study human genome lung cancer oncogenic proteins by Insilco methods.
The present work aims to study the proteins of oncogenes of lung cancer patients of the human genome. This is the first attempt made to analyze the genes of lung cancer. The NCBI oncogenic protein transcripts were obtained. They were analyzed by BLASTP method , the dendograms are compared and interpreted. There are 7 oncogenic proteins of Human genome identified and analyzed by us using BLASTP. The interpreted results show that they have maximum similarity with other oncogenic proteins of human cancers and other organisms.

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